Cargando…

Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation

The number of DNA double-strand breaks (DSBs) initiating meiotic recombination is elevated in Saccharomyces cerevisiae mutants that are globally defective in forming crossovers and synaptonemal complex (SC), a protein scaffold juxtaposing homologous chromosomes. These mutants thus appear to lack a n...

Descripción completa

Detalles Bibliográficos
Autores principales: Mu, Xiaojing, Murakami, Hajime, Mohibullah, Neeman, Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706706/
https://www.ncbi.nlm.nih.gov/pubmed/33184224
http://dx.doi.org/10.1101/gad.342873.120

Ejemplares similares