A six-amino-acid motif is a major determinant in functional evolution of HOX1 proteins

Gene duplication and divergence is a major driver in the emergence of evolutionary novelties. How variations in amino acid sequences lead to loss of ancestral activity and functional diversification of proteins is poorly understood. We used cross-species functional analysis of Drosophila Labial and...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Narendra Pratap, De Kumar, Bony, Paulson, Ariel, Parrish, Mark E., Zhang, Ying, Florens, Laurence, Conaway, Joan W., Si, Kausik, Krumlauf, Robb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706710/
https://www.ncbi.nlm.nih.gov/pubmed/33184220
http://dx.doi.org/10.1101/gad.342329.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706710/
https://www.ncbi.nlm.nih.gov/pubmed/33184220
http://dx.doi.org/10.1101/gad.342329.120

Ejemplares similares