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DUSP11-mediated control of 5′-triphosphate RNA regulates RIG-I sensitivity
Deciphering the mechanisms that regulate the sensitivity of pathogen recognition receptors is imperative to understanding infection and inflammation. Here we demonstrate that the RNA triphosphatase dual-specificity phosphatase 11 (DUSP11) acts on both host and virus-derived 5′-triphosphate RNAs rend...
Autores principales: | Choi, Joon H., Burke, James M., Szymanik, Kayla H., Nepal, Upasana, Battenhouse, Anna, Lau, Justin T., Stark, Aaron, Lam, Victor, Sullivan, Christopher S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706711/ https://www.ncbi.nlm.nih.gov/pubmed/33184222 http://dx.doi.org/10.1101/gad.340604.120 |
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