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Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time
The levels and subcellular localizations of proteins regulate critical aspects of many cellular processes and can become targets of therapeutic intervention. However, high-throughput methods for the discovery of proteins that change localization either by shuttling between compartments, by binding l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706735/ https://www.ncbi.nlm.nih.gov/pubmed/33203764 http://dx.doi.org/10.1101/gr.261503.120 |