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Experimental Infection of Cattle with SARS-CoV-2

We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 uninoculated cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The i...

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Detalles Bibliográficos
Autores principales: Ulrich, Lorenz, Wernike, Kerstin, Hoffmann, Donata, Mettenleiter, Thomas C., Beer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706945/
https://www.ncbi.nlm.nih.gov/pubmed/33034284
http://dx.doi.org/10.3201/eid2612.203799
Descripción
Sumario:We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 uninoculated cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.