Cargando…

Experimental Infection of Cattle with SARS-CoV-2

We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 uninoculated cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ulrich, Lorenz, Wernike, Kerstin, Hoffmann, Donata, Mettenleiter, Thomas C., Beer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706945/
https://www.ncbi.nlm.nih.gov/pubmed/33034284
http://dx.doi.org/10.3201/eid2612.203799
_version_ 1783617256081588224
author Ulrich, Lorenz
Wernike, Kerstin
Hoffmann, Donata
Mettenleiter, Thomas C.
Beer, Martin
author_facet Ulrich, Lorenz
Wernike, Kerstin
Hoffmann, Donata
Mettenleiter, Thomas C.
Beer, Martin
author_sort Ulrich, Lorenz
collection PubMed
description We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 uninoculated cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.
format Online
Article
Text
id pubmed-7706945
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-77069452020-12-08 Experimental Infection of Cattle with SARS-CoV-2 Ulrich, Lorenz Wernike, Kerstin Hoffmann, Donata Mettenleiter, Thomas C. Beer, Martin Emerg Infect Dis Dispatch We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 uninoculated cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected. Centers for Disease Control and Prevention 2020-12 /pmc/articles/PMC7706945/ /pubmed/33034284 http://dx.doi.org/10.3201/eid2612.203799 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ulrich, Lorenz
Wernike, Kerstin
Hoffmann, Donata
Mettenleiter, Thomas C.
Beer, Martin
Experimental Infection of Cattle with SARS-CoV-2
title Experimental Infection of Cattle with SARS-CoV-2
title_full Experimental Infection of Cattle with SARS-CoV-2
title_fullStr Experimental Infection of Cattle with SARS-CoV-2
title_full_unstemmed Experimental Infection of Cattle with SARS-CoV-2
title_short Experimental Infection of Cattle with SARS-CoV-2
title_sort experimental infection of cattle with sars-cov-2
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706945/
https://www.ncbi.nlm.nih.gov/pubmed/33034284
http://dx.doi.org/10.3201/eid2612.203799
work_keys_str_mv AT ulrichlorenz experimentalinfectionofcattlewithsarscov2
AT wernikekerstin experimentalinfectionofcattlewithsarscov2
AT hoffmanndonata experimentalinfectionofcattlewithsarscov2
AT mettenleiterthomasc experimentalinfectionofcattlewithsarscov2
AT beermartin experimentalinfectionofcattlewithsarscov2