Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recogn...

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Detalles Bibliográficos
Autores principales: Murakami, Shin, Kitamura, Tomoya, Suzuki, Jin, Sato, Ryouta, Aoi, Toshiki, Fujii, Marina, Matsugo, Hiromichi, Kamiki, Haruhiko, Ishida, Hiroho, Takenaka-Uema, Akiko, Shimojima, Masayuki, Horimoto, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706965/
https://www.ncbi.nlm.nih.gov/pubmed/33219796
http://dx.doi.org/10.3201/eid2612.203386
Descripción
Sumario:Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

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