Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide s...

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Autores principales: Morley, Gabriella L., Taylor, Stephen, Jossi, Sian, Perez-Toledo, Marisol, Faustini, Sian E., Marcial-Juarez, Edith, Shields, Adrian M., Goodall, Margaret, Allen, Joel D., Watanabe, Yasunori, Newby, Maddy L., Crispin, Max, Drayson, Mark T., Cunningham, Adam F., Richter, Alex G., O’Shea, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706975/
https://www.ncbi.nlm.nih.gov/pubmed/32969788
http://dx.doi.org/10.3201/eid2612.203309
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author Morley, Gabriella L.
Taylor, Stephen
Jossi, Sian
Perez-Toledo, Marisol
Faustini, Sian E.
Marcial-Juarez, Edith
Shields, Adrian M.
Goodall, Margaret
Allen, Joel D.
Watanabe, Yasunori
Newby, Maddy L.
Crispin, Max
Drayson, Mark T.
Cunningham, Adam F.
Richter, Alex G.
O’Shea, Matthew K.
author_facet Morley, Gabriella L.
Taylor, Stephen
Jossi, Sian
Perez-Toledo, Marisol
Faustini, Sian E.
Marcial-Juarez, Edith
Shields, Adrian M.
Goodall, Margaret
Allen, Joel D.
Watanabe, Yasunori
Newby, Maddy L.
Crispin, Max
Drayson, Mark T.
Cunningham, Adam F.
Richter, Alex G.
O’Shea, Matthew K.
author_sort Morley, Gabriella L.
collection PubMed
description Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.
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spelling pubmed-77069752020-12-08 Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples Morley, Gabriella L. Taylor, Stephen Jossi, Sian Perez-Toledo, Marisol Faustini, Sian E. Marcial-Juarez, Edith Shields, Adrian M. Goodall, Margaret Allen, Joel D. Watanabe, Yasunori Newby, Maddy L. Crispin, Max Drayson, Mark T. Cunningham, Adam F. Richter, Alex G. O’Shea, Matthew K. Emerg Infect Dis Dispatch Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic. Centers for Disease Control and Prevention 2020-12 /pmc/articles/PMC7706975/ /pubmed/32969788 http://dx.doi.org/10.3201/eid2612.203309 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Morley, Gabriella L.
Taylor, Stephen
Jossi, Sian
Perez-Toledo, Marisol
Faustini, Sian E.
Marcial-Juarez, Edith
Shields, Adrian M.
Goodall, Margaret
Allen, Joel D.
Watanabe, Yasunori
Newby, Maddy L.
Crispin, Max
Drayson, Mark T.
Cunningham, Adam F.
Richter, Alex G.
O’Shea, Matthew K.
Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title_full Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title_fullStr Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title_full_unstemmed Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title_short Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples
title_sort sensitive detection of sars-cov-2–specific antibodies in dried blood spot samples
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7706975/
https://www.ncbi.nlm.nih.gov/pubmed/32969788
http://dx.doi.org/10.3201/eid2612.203309
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