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The Role of the Gut Microbiota and the Immune System in the Development of Autism
Autism spectrum disorders (ASDs) are neurodevelopmental disorders that present with social skills and communication challenges, restricted interest, and repetitive behavior. The specific cause of autism is not well understood yet. However, n...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cureus
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707059/ https://www.ncbi.nlm.nih.gov/pubmed/33269154 http://dx.doi.org/10.7759/cureus.11226 |
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| author | Lungba, Rayan M Khan, Seyad Zulficar Ali Ajibawo-Aganbi, Uvie Perez Bastidas, Maria V Veliginti, Swathi Saleem, Sania Cancarevic, Ivan |
| author_facet | Lungba, Rayan M Khan, Seyad Zulficar Ali Ajibawo-Aganbi, Uvie Perez Bastidas, Maria V Veliginti, Swathi Saleem, Sania Cancarevic, Ivan |
| author_sort | Lungba, Rayan M |
| collection | PubMed |
| description | Autism spectrum disorders (ASDs) are neurodevelopmental disorders that present with social skills and communication challenges, restricted interest, and repetitive behavior. The specific cause of autism is not well understood yet. However, numerous studies indicated that environmental and genetic factors, dysregulated immune response, and alterations to the balance and content of the gut microbiota are implemented in the development of autism. Many non-pharmacological interventions are nominated to manage autism, including family support services and psychoeducational methods. Moreover, different pharmacological therapy modalities are recommended for children with ASD. Learning more about the brain, immune system, and gut connections could assist in early diagnosis and treatment of this devastating neurodevelopmental disorders as an early intervention in ASD could improve a child's overall development. We gathered data from relevant previously published articles on PubMed to evaluate the role of the gut microbiota and the immune system on the development of autism. |
| format | Online Article Text |
| id | pubmed-7707059 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Cureus |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77070592020-12-01 The Role of the Gut Microbiota and the Immune System in the Development of Autism Lungba, Rayan M Khan, Seyad Zulficar Ali Ajibawo-Aganbi, Uvie Perez Bastidas, Maria V Veliginti, Swathi Saleem, Sania Cancarevic, Ivan Cureus Family/General Practice Autism spectrum disorders (ASDs) are neurodevelopmental disorders that present with social skills and communication challenges, restricted interest, and repetitive behavior. The specific cause of autism is not well understood yet. However, numerous studies indicated that environmental and genetic factors, dysregulated immune response, and alterations to the balance and content of the gut microbiota are implemented in the development of autism. Many non-pharmacological interventions are nominated to manage autism, including family support services and psychoeducational methods. Moreover, different pharmacological therapy modalities are recommended for children with ASD. Learning more about the brain, immune system, and gut connections could assist in early diagnosis and treatment of this devastating neurodevelopmental disorders as an early intervention in ASD could improve a child's overall development. We gathered data from relevant previously published articles on PubMed to evaluate the role of the gut microbiota and the immune system on the development of autism. Cureus 2020-10-28 /pmc/articles/PMC7707059/ /pubmed/33269154 http://dx.doi.org/10.7759/cureus.11226 Text en Copyright © 2020, Lungba et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| spellingShingle | Family/General Practice Lungba, Rayan M Khan, Seyad Zulficar Ali Ajibawo-Aganbi, Uvie Perez Bastidas, Maria V Veliginti, Swathi Saleem, Sania Cancarevic, Ivan The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title | The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title_full | The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title_fullStr | The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title_full_unstemmed | The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title_short | The Role of the Gut Microbiota and the Immune System in the Development of Autism |
| title_sort | role of the gut microbiota and the immune system in the development of autism |
| topic | Family/General Practice |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707059/ https://www.ncbi.nlm.nih.gov/pubmed/33269154 http://dx.doi.org/10.7759/cureus.11226 |
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