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Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans
BACKGROUND AND PURPOSE: There is a clear need for innovation in anti‐tuberculosis drug development. The zebrafish larva is an attractive disease model in tuberculosis research. To translate pharmacological findings to higher vertebrates, including humans, the internal exposure of drugs needs to be q...
Autores principales: | van Wijk, Rob C., Hu, Wanbin, Dijkema, Sharka M., van den Berg, Dirk‐Jan, Liu, Jeremy, Bahi, Rida, Verbeek, Fons J., Simonsson, Ulrika S.H., Spaink, Herman P., van der Graaf, Piet H., Krekels, Elke H.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707096/ https://www.ncbi.nlm.nih.gov/pubmed/32860631 http://dx.doi.org/10.1111/bph.15247 |
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