Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice

The dysregulation of myeloid-derived cell metabolism can drive atherosclerosis. AMP-activated protein kinase (AMPK) controls various aspects of macrophage dynamics and lipid homeostasis, which are important during atherogenesis. Using LysM-Cre to drive the deletion of both the α1 and α2 catalytic su...

Descripción completa

Detalles Bibliográficos
Autores principales: LeBlond, Nicholas D., Ghorbani, Peyman, O’Dwyer, Conor, Ambursley, Nia, Nunes, Julia R. C., Smith, Tyler K. T., Trzaskalski, Natasha A., Mulvihill, Erin E., Viollet, Benoit, Foretz, Marc, Fullerton, Morgan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707174/
https://www.ncbi.nlm.nih.gov/pubmed/32978273
http://dx.doi.org/10.1194/jlr.RA120001040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707174/
https://www.ncbi.nlm.nih.gov/pubmed/32978273
http://dx.doi.org/10.1194/jlr.RA120001040

Ejemplares similares