Cargando…

Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice

Microsomal triglyceride transfer protein (MTTP) deficiency results in a syndrome of hypolipidemia and accelerated NAFLD. Animal models of decreased hepatic MTTP activity have revealed an unexplained dissociation between hepatic steatosis and hepatic insulin resistance. Here, we performed comprehensi...

Descripción completa

Detalles Bibliográficos
Autores principales: Abulizi, Abudukadier, Vatner, Daniel F., Ye, Zhang, Wang, Yongliang, Camporez, Joao-Paulo, Zhang, Dongyan, Kahn, Mario, Lyu, Kun, Sirwi, Alaa, Cline, Gary W., Hussain, M. Mahmood, Aspichueta, Patricia, Samuel, Varman T., Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707176/
https://www.ncbi.nlm.nih.gov/pubmed/32907986
http://dx.doi.org/10.1194/jlr.RA119000586

Ejemplares similares