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Curvature-processing domains in primate V4
Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707829/ https://www.ncbi.nlm.nih.gov/pubmed/33211007 http://dx.doi.org/10.7554/eLife.57502 |
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author | Tang, Rendong Song, Qianling Li, Ying Zhang, Rui Cai, Xingya Lu, Haidong D |
author_facet | Tang, Rendong Song, Qianling Li, Ying Zhang, Rui Cai, Xingya Lu, Haidong D |
author_sort | Tang, Rendong |
collection | PubMed |
description | Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4 that contained neurons preferring curved contours over rectilinear ones. These curvature domains had similar sizes and response amplitudes as orientation domains but tended to separate from these regions. Within the curvature domains, neurons that preferred circles or curve orientations clustered further into finer scale subdomains. Nevertheless, individual neurons also had a wide range of contour selectivity, and neighboring neurons exhibited a substantial diversity in shape tuning besides their common shape preferences. In strong contrast to V4, V1 and V2 did not have such contour-shape-related domains. These findings highlight the importance and complexity of curvature processing in visual object recognition and the key functional role of V4 in this process. |
format | Online Article Text |
id | pubmed-7707829 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-77078292020-12-02 Curvature-processing domains in primate V4 Tang, Rendong Song, Qianling Li, Ying Zhang, Rui Cai, Xingya Lu, Haidong D eLife Neuroscience Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4 that contained neurons preferring curved contours over rectilinear ones. These curvature domains had similar sizes and response amplitudes as orientation domains but tended to separate from these regions. Within the curvature domains, neurons that preferred circles or curve orientations clustered further into finer scale subdomains. Nevertheless, individual neurons also had a wide range of contour selectivity, and neighboring neurons exhibited a substantial diversity in shape tuning besides their common shape preferences. In strong contrast to V4, V1 and V2 did not have such contour-shape-related domains. These findings highlight the importance and complexity of curvature processing in visual object recognition and the key functional role of V4 in this process. eLife Sciences Publications, Ltd 2020-11-19 /pmc/articles/PMC7707829/ /pubmed/33211007 http://dx.doi.org/10.7554/eLife.57502 Text en © 2020, Tang et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Tang, Rendong Song, Qianling Li, Ying Zhang, Rui Cai, Xingya Lu, Haidong D Curvature-processing domains in primate V4 |
title | Curvature-processing domains in primate V4 |
title_full | Curvature-processing domains in primate V4 |
title_fullStr | Curvature-processing domains in primate V4 |
title_full_unstemmed | Curvature-processing domains in primate V4 |
title_short | Curvature-processing domains in primate V4 |
title_sort | curvature-processing domains in primate v4 |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707829/ https://www.ncbi.nlm.nih.gov/pubmed/33211007 http://dx.doi.org/10.7554/eLife.57502 |
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