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Curvature-processing domains in primate V4

Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4...

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Autores principales: Tang, Rendong, Song, Qianling, Li, Ying, Zhang, Rui, Cai, Xingya, Lu, Haidong D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707829/
https://www.ncbi.nlm.nih.gov/pubmed/33211007
http://dx.doi.org/10.7554/eLife.57502
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author Tang, Rendong
Song, Qianling
Li, Ying
Zhang, Rui
Cai, Xingya
Lu, Haidong D
author_facet Tang, Rendong
Song, Qianling
Li, Ying
Zhang, Rui
Cai, Xingya
Lu, Haidong D
author_sort Tang, Rendong
collection PubMed
description Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4 that contained neurons preferring curved contours over rectilinear ones. These curvature domains had similar sizes and response amplitudes as orientation domains but tended to separate from these regions. Within the curvature domains, neurons that preferred circles or curve orientations clustered further into finer scale subdomains. Nevertheless, individual neurons also had a wide range of contour selectivity, and neighboring neurons exhibited a substantial diversity in shape tuning besides their common shape preferences. In strong contrast to V4, V1 and V2 did not have such contour-shape-related domains. These findings highlight the importance and complexity of curvature processing in visual object recognition and the key functional role of V4 in this process.
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spelling pubmed-77078292020-12-02 Curvature-processing domains in primate V4 Tang, Rendong Song, Qianling Li, Ying Zhang, Rui Cai, Xingya Lu, Haidong D eLife Neuroscience Neurons in primate V4 exhibit various types of selectivity for contour shapes, including curves, angles, and simple shapes. How are these neurons organized in V4 remains unclear. Using intrinsic signal optical imaging and two-photon calcium imaging, we observed submillimeter functional domains in V4 that contained neurons preferring curved contours over rectilinear ones. These curvature domains had similar sizes and response amplitudes as orientation domains but tended to separate from these regions. Within the curvature domains, neurons that preferred circles or curve orientations clustered further into finer scale subdomains. Nevertheless, individual neurons also had a wide range of contour selectivity, and neighboring neurons exhibited a substantial diversity in shape tuning besides their common shape preferences. In strong contrast to V4, V1 and V2 did not have such contour-shape-related domains. These findings highlight the importance and complexity of curvature processing in visual object recognition and the key functional role of V4 in this process. eLife Sciences Publications, Ltd 2020-11-19 /pmc/articles/PMC7707829/ /pubmed/33211007 http://dx.doi.org/10.7554/eLife.57502 Text en © 2020, Tang et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Tang, Rendong
Song, Qianling
Li, Ying
Zhang, Rui
Cai, Xingya
Lu, Haidong D
Curvature-processing domains in primate V4
title Curvature-processing domains in primate V4
title_full Curvature-processing domains in primate V4
title_fullStr Curvature-processing domains in primate V4
title_full_unstemmed Curvature-processing domains in primate V4
title_short Curvature-processing domains in primate V4
title_sort curvature-processing domains in primate v4
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707829/
https://www.ncbi.nlm.nih.gov/pubmed/33211007
http://dx.doi.org/10.7554/eLife.57502
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AT caixingya curvatureprocessingdomainsinprimatev4
AT luhaidongd curvatureprocessingdomainsinprimatev4