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Stretching DNA origami: effect of nicks and Holliday junctions on the axial stiffness

The axial stiffness of DNA origami is determined as a function of key nanostructural characteristics. Different constructs of two-helix nanobeams with specified densities of nicks and Holliday junctions are synthesized and stretched by fluid flow. Implementing single particle tracking to extract for...

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Detalles Bibliográficos
Autores principales:	Jung, Wei-Hung, Chen, Enze, Veneziano, Remi, Gaitanaros, Stavros, Chen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708044/ https://www.ncbi.nlm.nih.gov/pubmed/33152066 http://dx.doi.org/10.1093/nar/gkaa985

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