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The role of FACT in managing chromatin: disruption, assembly, or repair?
FACT (FAcilitates Chromatin Transcription) has long been considered to be a transcription elongation factor whose ability to destabilize nucleosomes promotes RNAPII progression on chromatin templates. However, this is just one function of this histone chaperone, as FACT also functions in DNA replica...
Autores principales: | Formosa, Tim, Winston, Fred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708052/ https://www.ncbi.nlm.nih.gov/pubmed/33104782 http://dx.doi.org/10.1093/nar/gkaa912 |
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