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Structural distinctions between NAD(+) riboswitch domains 1 and 2 determine differential folding and ligand binding

Riboswitches are important gene regulatory elements frequently encountered in bacterial mRNAs. The recently discovered nadA riboswitch contains two similar, tandemly arrayed aptamer domains, with the first domain possessing high affinity for nicotinamide adenine dinucleotide (NAD(+)). The second dom...

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Detalles Bibliográficos
Autores principales:	Chen, Hao, Egger, Michaela, Xu, Xiaochen, Flemmich, Laurin, Krasheninina, Olga, Sun, Aiai, Micura, Ronald, Ren, Aiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708056/ https://www.ncbi.nlm.nih.gov/pubmed/33170270 http://dx.doi.org/10.1093/nar/gkaa1029

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