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Histone sumoylation promotes Set3 histone-deacetylase complex-mediated transcriptional regulation
Histones are substrates of the SUMO (small ubiquitin-like modifier) conjugation pathway. Several reports suggest histone sumoylation affects transcription negatively, but paradoxically, our genome-wide analysis shows the modification concentrated at many active genes. We find that trans-tail regulat...
Autores principales: | Ryu, Hong-Yeoul, Zhao, Dejian, Li, Jianhui, Su, Dan, Hochstrasser, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708062/ https://www.ncbi.nlm.nih.gov/pubmed/33231641 http://dx.doi.org/10.1093/nar/gkaa1093 |
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