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ASHIC: hierarchical Bayesian modeling of diploid chromatin contacts and structures

The recently developed Hi-C technique has been widely applied to map genome-wide chromatin interactions. However, current methods for analyzing diploid Hi-C data cannot fully distinguish between homologous chromosomes. Consequently, the existing diploid Hi-C analyses are based on sparse and inaccura...

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Detalles Bibliográficos
Autores principales: Ye, Tiantian, Ma, Wenxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708071/
https://www.ncbi.nlm.nih.gov/pubmed/33074315
http://dx.doi.org/10.1093/nar/gkaa872