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The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination

Meiotic recombination enables reciprocal exchange of genetic information between parental chromosomes and is essential for fertility. MEIOB, a meiosis-specific ssDNA-binding protein, regulates early meiotic recombination. Here we report that the human infertility-associated missense mutation (N64I)...

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Detalles Bibliográficos
Autores principales:	Guo, Rui, Xu, Yang, Leu, N Adrian, Zhang, Lei, Fuchs, Serge Y, Ye, Lan, Wang, P Jeremy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708077/ https://www.ncbi.nlm.nih.gov/pubmed/33166385 http://dx.doi.org/10.1093/nar/gkaa1016

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