MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis

BACKGROUND: To investigate the odonto-immunomodulatory properties of dental pulp stem cell-derived small extracellular vesicles (DPSCs-sEV), which promote odontogenesis by switching macrophages toward the pro-healing M2 phenotype. METHODS: MicroRNA sequencing was carried out for microRNA profiling o...

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Detalles Bibliográficos
Autores principales: Zheng, Jianmao, Kong, Yuanyuan, Hu, Xiaoli, Li, Zhishan, Li, Yaoyin, Zhong, Yingqun, Wei, Xi, Ling, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708107/
https://www.ncbi.nlm.nih.gov/pubmed/33256846
http://dx.doi.org/10.1186/s13287-020-02039-1

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