Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity

Granzyme B (GrB) is a serine protease produced by immune and non-immune cells, able to promote multiple processes, like apoptosis, inflammation, extracellular matrix remodeling and fibrosis. GrB expression in visceral adipose tissue (VAT) was associated with tissue damage, local inflammation and ins...

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Detalles Bibliográficos
Autores principales: Cimini, Flavia Agata, Barchetta, Ilaria, Ceccarelli, Valentina, Chiappetta, Caterina, Di Biasio, Alberto, Bertoccini, Laura, Sentinelli, Federica, Leonetti, Frida, Silecchia, Gianfranco, Di Cristofano, Claudio, Baroni, Marco Giorgio, Velotti, Francesca, Cavallo, Maria Gisella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708321/
https://www.ncbi.nlm.nih.gov/pubmed/33312176
http://dx.doi.org/10.3389/fimmu.2020.589188

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