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Hippocampal adult-born granule cells drive network activity in a mouse model of chronic temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is characterized by recurrent seizures driven by synchronous neuronal activity. The reorganization of the dentate gyrus (DG) in TLE may create pathological conduction pathways for synchronous discharges in the temporal lobe, though critical microcircuit-level detail is m...
Autores principales: | Sparks, F. T., Liao, Z., Li, W., Grosmark, A., Soltesz, I., Losonczy, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708476/ https://www.ncbi.nlm.nih.gov/pubmed/33262339 http://dx.doi.org/10.1038/s41467-020-19969-2 |
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