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Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis
Metabolic syndrome (MetS) has increasingly gained importance as the main risk factor for cardiovascular diseases and type II diabetes mellitus. Various natural compounds derived from plants are associated with beneficial effects on the incidence and progression of MetS. This study aimed to evaluate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708630/ https://www.ncbi.nlm.nih.gov/pubmed/33262398 http://dx.doi.org/10.1038/s41598-020-77983-2 |
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author | Jang, Hwan-Hee Lee, Jounghee Lee, Sung-Hyen Lee, Young-Min |
author_facet | Jang, Hwan-Hee Lee, Jounghee Lee, Sung-Hyen Lee, Young-Min |
author_sort | Jang, Hwan-Hee |
collection | PubMed |
description | Metabolic syndrome (MetS) has increasingly gained importance as the main risk factor for cardiovascular diseases and type II diabetes mellitus. Various natural compounds derived from plants are associated with beneficial effects on the incidence and progression of MetS. This study aimed to evaluate the effects of Capsicum annuum on factors related to MetS by assessing randomized controlled trials (written in English). We searched the online databases of PubMed, Embase, Google scholar, and Cochrane Library up to April 2020. ‘Patient/Population, Intervention, Comparison and Outcomes’ format was used to determine whether intervention with C. annuum supplementation compared with placebo supplementation had any effect on the components of MetS among participants. We considered standardized mean differences (SMD) with 95% confidence intervals (CI) as effect size measures using random-effects model. Analysis of the included 11 studies (n = 609) showed that C. annuum supplementation had significant effect on low density lipoprotein-cholesterol [SMD = − 0.39; 95% CI − 0.72, − 0.07; P = 0.02; prediction interval, − 1.28 to 0.50] and marginally significant effect on body weight [SMD = − 0.19; 95% CI − 0.40, 0.03; P = 0.09]. However, larger and well-designed clinical trials are needed to investigate the effects of C. annuum on MetS. |
format | Online Article Text |
id | pubmed-7708630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-77086302020-12-03 Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis Jang, Hwan-Hee Lee, Jounghee Lee, Sung-Hyen Lee, Young-Min Sci Rep Article Metabolic syndrome (MetS) has increasingly gained importance as the main risk factor for cardiovascular diseases and type II diabetes mellitus. Various natural compounds derived from plants are associated with beneficial effects on the incidence and progression of MetS. This study aimed to evaluate the effects of Capsicum annuum on factors related to MetS by assessing randomized controlled trials (written in English). We searched the online databases of PubMed, Embase, Google scholar, and Cochrane Library up to April 2020. ‘Patient/Population, Intervention, Comparison and Outcomes’ format was used to determine whether intervention with C. annuum supplementation compared with placebo supplementation had any effect on the components of MetS among participants. We considered standardized mean differences (SMD) with 95% confidence intervals (CI) as effect size measures using random-effects model. Analysis of the included 11 studies (n = 609) showed that C. annuum supplementation had significant effect on low density lipoprotein-cholesterol [SMD = − 0.39; 95% CI − 0.72, − 0.07; P = 0.02; prediction interval, − 1.28 to 0.50] and marginally significant effect on body weight [SMD = − 0.19; 95% CI − 0.40, 0.03; P = 0.09]. However, larger and well-designed clinical trials are needed to investigate the effects of C. annuum on MetS. Nature Publishing Group UK 2020-12-01 /pmc/articles/PMC7708630/ /pubmed/33262398 http://dx.doi.org/10.1038/s41598-020-77983-2 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Jang, Hwan-Hee Lee, Jounghee Lee, Sung-Hyen Lee, Young-Min Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title | Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title_full | Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title_fullStr | Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title_full_unstemmed | Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title_short | Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
title_sort | effects of capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708630/ https://www.ncbi.nlm.nih.gov/pubmed/33262398 http://dx.doi.org/10.1038/s41598-020-77983-2 |
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