A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a macrophage-specific lncRNA MAARS (Macrophage-Associated Atherosclerosis lncRNA Sequence). Aortic intima expression of...

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Detalles Bibliográficos
Autores principales: Simion, Viorel, Zhou, Haoyang, Haemmig, Stefan, Pierce, Jacob B., Mendes, Shanelle, Tesmenitsky, Yevgenia, Pérez-Cremades, Daniel, Lee, James F., Chen, Alex F., Ronda, Nicoletta, Papotti, Bianca, Marto, Jarrod A., Feinberg, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708640/
https://www.ncbi.nlm.nih.gov/pubmed/33262333
http://dx.doi.org/10.1038/s41467-020-19664-2

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