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Quantitative modeling predicts mechanistic links between pre-treatment microbiome composition and metronidazole efficacy in bacterial vaginosis

Bacterial vaginosis is a condition associated with adverse reproductive outcomes and characterized by a shift from a Lactobacillus-dominant vaginal microbiota to a polymicrobial microbiota, consistently colonized by strains of Gardnerella vaginalis. Metronidazole is the first-line treatment; however...

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Detalles Bibliográficos
Autores principales:	Lee, Christina Y., Cheu, Ryan K., Lemke, Melissa M., Gustin, Andrew T., France, Michael T., Hampel, Benjamin, Thurman, Andrea R., Doncel, Gustavo F., Ravel, Jacques, Klatt, Nichole R., Arnold, Kelly B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708644/ https://www.ncbi.nlm.nih.gov/pubmed/33262350 http://dx.doi.org/10.1038/s41467-020-19880-w

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