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An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies

Explosion of gene therapy approaches for treating rare monogenic and common liver disorders created an urgent need for disease models able to replicate human liver cellular environment. Available models lack 3D liver structure or are unable to survive in long-term culture. We aimed to generate and t...

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Detalles Bibliográficos
Autores principales:	Lorvellec, Maëlle, Pellegata, Alessandro Filippo, Maestri, Alice, Turchetta, Chiara, Alvarez Mediavilla, Elena, Shibuya, Soichi, Jones, Brendan, Scottoni, Federico, Perocheau, Dany P., Cozmescu, Andrei Claudiu, Delhove, Juliette M., Kysh, Daniel, Gjinovci, Asllan, Counsell, John R., Heywood, Wendy E., Mills, Kevin, McKay, Tristan R., De Coppi, Paolo, Gissen, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708813/ https://www.ncbi.nlm.nih.gov/pubmed/33305175 http://dx.doi.org/10.1016/j.isci.2020.101808

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