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Role of PARP1-mediated autophagy in EGFR-TKI resistance in non-small cell lung cancer

Resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has become the main clinical challenge of advanced lung cancer. This research aimed to explore the role of PARP1-mediated autophagy in the progression of TKI therapy. PARP1-mediated autophagy was evaluated in vitro...

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Detalles Bibliográficos
Autores principales: Zhang, Zhimin, Lian, Xiaojuan, Xie, Wei, Quan, Jin, Liao, Maojun, Wu, Yan, Yang, Zhen-Zhou, Wang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708842/
https://www.ncbi.nlm.nih.gov/pubmed/33262410
http://dx.doi.org/10.1038/s41598-020-77908-z