Cargando…
Role of PARP1-mediated autophagy in EGFR-TKI resistance in non-small cell lung cancer
Resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has become the main clinical challenge of advanced lung cancer. This research aimed to explore the role of PARP1-mediated autophagy in the progression of TKI therapy. PARP1-mediated autophagy was evaluated in vitro...
Autores principales: | Zhang, Zhimin, Lian, Xiaojuan, Xie, Wei, Quan, Jin, Liao, Maojun, Wu, Yan, Yang, Zhen-Zhou, Wang, Ge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708842/ https://www.ncbi.nlm.nih.gov/pubmed/33262410 http://dx.doi.org/10.1038/s41598-020-77908-z |
Ejemplares similares
-
Combining EGFR-TKI With SAHA Overcomes EGFR-TKI-Acquired Resistance by Reducing the Protective Autophagy in Non-Small Cell Lung Cancer
por: Cao, Peijun, et al.
Publicado: (2022) -
BDH1 promotes lung cancer cell proliferation and metastases by PARP1‐mediated autophagy
por: Zhang, Zhimin, et al.
Publicado: (2023) -
Determining EGFR-TKI sensitivity of G719X and other uncommon EGFR mutations in non-small cell lung cancer: Perplexity and solution
por: Li, Kaidi, et al.
Publicado: (2017) -
Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer
por: Osude, Chike, et al.
Publicado: (2022) -
Low‑dose anlotinib combined with EGFR‑TKI can be used as an alternative for EGFR‑TKI‑resistant non‑small cell lung cancer in elderly patients
por: Chen, Yi, et al.
Publicado: (2023)