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Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

BACKGROUND: Diversity of the CRISPR locus of Mycobacterium tuberculosis complex has been studied since 1997 for molecular epidemiology purposes. By targeting solely the 43 spacers present in the two first sequenced genomes (H37Rv and BCG), it gave a biased idea of CRISPR diversity and ignored divers...

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Detalles Bibliográficos
Autores principales:	Refrégier, Guislaine, Sola, Christophe, Guyeux, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708916/ https://www.ncbi.nlm.nih.gov/pubmed/33256602 http://dx.doi.org/10.1186/s12864-020-07178-6

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