Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have bee...

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Autores principales: Hanifa, Munsoor A, Skott, Martin, Maltesen, Raluca G, Rasmussen, Bodil S, Nielsen, Søren, Frøkiær, Jørgen, Ring, Troels, Wimmer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708935/
https://www.ncbi.nlm.nih.gov/pubmed/33304964
http://dx.doi.org/10.1016/j.dib.2020.106567
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author Hanifa, Munsoor A
Skott, Martin
Maltesen, Raluca G
Rasmussen, Bodil S
Nielsen, Søren
Frøkiær, Jørgen
Ring, Troels
Wimmer, Reinhard
author_facet Hanifa, Munsoor A
Skott, Martin
Maltesen, Raluca G
Rasmussen, Bodil S
Nielsen, Søren
Frøkiær, Jørgen
Ring, Troels
Wimmer, Reinhard
author_sort Hanifa, Munsoor A
collection PubMed
description Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have been reported elsewhere (https://doi.org/10.1007/s11306-019-1569-3[1]). The data could be useful to researchers working with human CKD or rat models of the disease. In addition, several different types of NMR spectra were recorded, including 1D NOESY, CPMG, and 2D J-resolved spectra, and the data could be useful for method comparison and algorithm development, both in terms of NMR spectroscopy and multivariate analysis.
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spelling pubmed-77089352020-12-09 Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease Hanifa, Munsoor A Skott, Martin Maltesen, Raluca G Rasmussen, Bodil S Nielsen, Søren Frøkiær, Jørgen Ring, Troels Wimmer, Reinhard Data Brief Data Article Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have been reported elsewhere (https://doi.org/10.1007/s11306-019-1569-3[1]). The data could be useful to researchers working with human CKD or rat models of the disease. In addition, several different types of NMR spectra were recorded, including 1D NOESY, CPMG, and 2D J-resolved spectra, and the data could be useful for method comparison and algorithm development, both in terms of NMR spectroscopy and multivariate analysis. Elsevier 2020-11-23 /pmc/articles/PMC7708935/ /pubmed/33304964 http://dx.doi.org/10.1016/j.dib.2020.106567 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Hanifa, Munsoor A
Skott, Martin
Maltesen, Raluca G
Rasmussen, Bodil S
Nielsen, Søren
Frøkiær, Jørgen
Ring, Troels
Wimmer, Reinhard
Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title_full Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title_fullStr Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title_full_unstemmed Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title_short Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
title_sort tissue, urine and serum nmr metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708935/
https://www.ncbi.nlm.nih.gov/pubmed/33304964
http://dx.doi.org/10.1016/j.dib.2020.106567
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