CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer

SIMPLE SUMMARY: Prostate cancer (PCa) is the most common cancer in men and the second highest contributor to cancer deaths. Targeting lipid catabolism enzymes in PCa may offer new avenues for therapeutic approaches. During the last decade, carnitine palmitoyl transferase I (CPT1A) has been identifie...

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Detalles Bibliográficos
Autores principales: Joshi, Molishree, Kim, Jihye, D’Alessandro, Angelo, Monk, Emily, Bruce, Kimberley, Elajaili, Hanan, Nozik-Grayck, Eva, Goodspeed, Andrew, Costello, James C., Schlaepfer, Isabel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709014/
https://www.ncbi.nlm.nih.gov/pubmed/33218188
http://dx.doi.org/10.3390/cancers12113431

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