Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific

Bispecific molecules are biologically significant, yet their complex structures pose important manufacturing and pharmacokinetic challenges. Nevertheless, owing to similarities with monoclonal antibodies (mAbs), IgG-like bispecifics conceptually align well with conventional expression and manufactur...

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Detalles Bibliográficos
Autores principales: Ramasubramanian, Anusuya, Tennyson, Rachel, Magnay, Maureen, Kathuria, Sagar, Travaline, Tara, Jain, Annu, Lord, Dana M., Salemi, Megan, Sullivan, Caitlin, Magnay, Tristan, Hu, Jiali, Bric-Furlong, Eva, Rival, Pierrick, Zhou, Yanfeng, Hoffmann, Dietmar, Brondyk, William, Radošević, Katarina, Chowdhury, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709125/
https://www.ncbi.nlm.nih.gov/pubmed/33172091
http://dx.doi.org/10.3390/antib9040062

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