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Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures
Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious implementation and relaxation of restrictions amplify their public health benefits while reducing costs. We derive optimal strategies for togg...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709193/ https://www.ncbi.nlm.nih.gov/pubmed/33269372 http://dx.doi.org/10.1101/2020.11.26.20152520 |
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author | Yang, Haoxiang Sürer, Özge Duque, Daniel Morton, David P. Singh, Bismark Fox, Spencer J. Pasco, Remy Pierce, Kelly Rathouz, Paul Du, Zhanwei Pignone, Michael Escott, Mark E. Adler, Stephen I. Johnston, S. Claiborne Meyers, Lauren Ancel |
author_facet | Yang, Haoxiang Sürer, Özge Duque, Daniel Morton, David P. Singh, Bismark Fox, Spencer J. Pasco, Remy Pierce, Kelly Rathouz, Paul Du, Zhanwei Pignone, Michael Escott, Mark E. Adler, Stephen I. Johnston, S. Claiborne Meyers, Lauren Ancel |
author_sort | Yang, Haoxiang |
collection | PubMed |
description | Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious implementation and relaxation of restrictions amplify their public health benefits while reducing costs. We derive optimal strategies for toggling between mitigation stages using daily COVID-19 hospital admissions. With public compliance, the policy triggers ensure adequate intensive care unit capacity with high probability while minimizing the duration of strict mitigation measures. In comparison, we show that other sensible COVID-19 staging policies, including France’s ICU-based thresholds and a widely adopted indicator for reopening schools and businesses, require overly restrictive measures or trigger strict stages too late to avert catastrophic surges. As cities worldwide face future pandemic waves, our findings provide a robust strategy for tracking COVID-19 hospital admissions as an early indicator of hospital surges and enacting staged measures to ensure integrity of the health system, safety of the health workforce, and public confidence. |
format | Online Article Text |
id | pubmed-7709193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-77091932020-12-03 Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures Yang, Haoxiang Sürer, Özge Duque, Daniel Morton, David P. Singh, Bismark Fox, Spencer J. Pasco, Remy Pierce, Kelly Rathouz, Paul Du, Zhanwei Pignone, Michael Escott, Mark E. Adler, Stephen I. Johnston, S. Claiborne Meyers, Lauren Ancel medRxiv Article Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious implementation and relaxation of restrictions amplify their public health benefits while reducing costs. We derive optimal strategies for toggling between mitigation stages using daily COVID-19 hospital admissions. With public compliance, the policy triggers ensure adequate intensive care unit capacity with high probability while minimizing the duration of strict mitigation measures. In comparison, we show that other sensible COVID-19 staging policies, including France’s ICU-based thresholds and a widely adopted indicator for reopening schools and businesses, require overly restrictive measures or trigger strict stages too late to avert catastrophic surges. As cities worldwide face future pandemic waves, our findings provide a robust strategy for tracking COVID-19 hospital admissions as an early indicator of hospital surges and enacting staged measures to ensure integrity of the health system, safety of the health workforce, and public confidence. Cold Spring Harbor Laboratory 2020-12-24 /pmc/articles/PMC7709193/ /pubmed/33269372 http://dx.doi.org/10.1101/2020.11.26.20152520 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator. |
spellingShingle | Article Yang, Haoxiang Sürer, Özge Duque, Daniel Morton, David P. Singh, Bismark Fox, Spencer J. Pasco, Remy Pierce, Kelly Rathouz, Paul Du, Zhanwei Pignone, Michael Escott, Mark E. Adler, Stephen I. Johnston, S. Claiborne Meyers, Lauren Ancel Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title | Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title_full | Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title_fullStr | Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title_full_unstemmed | Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title_short | Design of COVID-19 Staged Alert Systems to Ensure Healthcare Capacity with Minimal Closures |
title_sort | design of covid-19 staged alert systems to ensure healthcare capacity with minimal closures |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709193/ https://www.ncbi.nlm.nih.gov/pubmed/33269372 http://dx.doi.org/10.1101/2020.11.26.20152520 |
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