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High-performance macromolecular data delivery and visualization for the web
Biomacromolecular structural data make up a vital and crucial scientific resource that has grown not only in terms of its amount but also in its size and complexity. Furthermore, these data are accompanied by large and increasing amounts of experimental data. Additionally, the macromolecular data ar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709201/ https://www.ncbi.nlm.nih.gov/pubmed/33263322 http://dx.doi.org/10.1107/S2059798320014515 |
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author | Sehnal, David Svobodová, Radka Berka, Karel Rose, Alexander S. Burley, Stephen K. Velankar, Sameer Koča, Jaroslav |
author_facet | Sehnal, David Svobodová, Radka Berka, Karel Rose, Alexander S. Burley, Stephen K. Velankar, Sameer Koča, Jaroslav |
author_sort | Sehnal, David |
collection | PubMed |
description | Biomacromolecular structural data make up a vital and crucial scientific resource that has grown not only in terms of its amount but also in its size and complexity. Furthermore, these data are accompanied by large and increasing amounts of experimental data. Additionally, the macromolecular data are enriched with value-added annotations describing their biological, physicochemical and structural properties. Today, the scientific community requires fast and fully interactive web visualization to exploit this complex structural information. This article provides a survey of the available cutting-edge web services that address this challenge. Specifically, it focuses on data-delivery problems, discusses the visualization of a single structure, including experimental data and annotations, and concludes with a focus on the results of molecular-dynamics simulations and the visualization of structural ensembles. |
format | Online Article Text |
id | pubmed-7709201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-77092012020-12-09 High-performance macromolecular data delivery and visualization for the web Sehnal, David Svobodová, Radka Berka, Karel Rose, Alexander S. Burley, Stephen K. Velankar, Sameer Koča, Jaroslav Acta Crystallogr D Struct Biol Ccp4 Biomacromolecular structural data make up a vital and crucial scientific resource that has grown not only in terms of its amount but also in its size and complexity. Furthermore, these data are accompanied by large and increasing amounts of experimental data. Additionally, the macromolecular data are enriched with value-added annotations describing their biological, physicochemical and structural properties. Today, the scientific community requires fast and fully interactive web visualization to exploit this complex structural information. This article provides a survey of the available cutting-edge web services that address this challenge. Specifically, it focuses on data-delivery problems, discusses the visualization of a single structure, including experimental data and annotations, and concludes with a focus on the results of molecular-dynamics simulations and the visualization of structural ensembles. International Union of Crystallography 2020-11-26 /pmc/articles/PMC7709201/ /pubmed/33263322 http://dx.doi.org/10.1107/S2059798320014515 Text en © Sehnal et al. 2020 http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Ccp4 Sehnal, David Svobodová, Radka Berka, Karel Rose, Alexander S. Burley, Stephen K. Velankar, Sameer Koča, Jaroslav High-performance macromolecular data delivery and visualization for the web |
title | High-performance macromolecular data delivery and visualization for the web |
title_full | High-performance macromolecular data delivery and visualization for the web |
title_fullStr | High-performance macromolecular data delivery and visualization for the web |
title_full_unstemmed | High-performance macromolecular data delivery and visualization for the web |
title_short | High-performance macromolecular data delivery and visualization for the web |
title_sort | high-performance macromolecular data delivery and visualization for the web |
topic | Ccp4 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709201/ https://www.ncbi.nlm.nih.gov/pubmed/33263322 http://dx.doi.org/10.1107/S2059798320014515 |
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