Shotgun proteomics coupled to nanoparticle-based biomarker enrichment reveals a novel panel of extracellular matrix proteins as candidate serum protein biomarkers for early-stage breast cancer detection

BACKGROUND: The lack of specificity and high degree of false positive and false negative rates when using mammographic screening for detecting early-stage breast cancer is a critical issue. Blood-based molecular assays that could be used in adjunct with mammography for increased specificity and sens...

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Detalles Bibliográficos
Autores principales: Fredolini, Claudia, Pathak, Khyatiben V., Paris, Luisa, Chapple, Kristina M., Tsantilas, Kristine A., Rosenow, Matthew, Tegeler, Tony J., Garcia-Mansfield, Krystine, Tamburro, Davide, Zhou, Weidong, Russo, Paul, Massarut, Samuele, Facchiano, Francesco, Belluco, Claudio, De Maria, Ruggero, Garaci, Enrico, Liotta, Lance, Petricoin, Emanuel F., Pirrotte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709252/
https://www.ncbi.nlm.nih.gov/pubmed/33267867
http://dx.doi.org/10.1186/s13058-020-01373-9

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