Cargando…
Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature
BACKGROUND: Gastric carcinoma (GC) with second primary malignancy (SPM) is the most frequent combination within the multiple primary malignancies (MPM) group. The presentation of a GC associated with a synchronized SPM in the kidney is extremely rare and unusual. This study presents a rare case of s...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709286/ https://www.ncbi.nlm.nih.gov/pubmed/33261664 http://dx.doi.org/10.1186/s13256-020-02576-6 |
_version_ | 1783617717135212544 |
---|---|
author | Martín-Pérez, J. A. Torres-Silva, C. Tenorio-Arguelles, R. García-Corona, D. A. Silva-González, S. Dominguez-Rodriguez, J. A. De Alba-Cruz, I. Nagore-Ancona, J. F. González-Luna, J. A. López-Bochm, K. A. |
author_facet | Martín-Pérez, J. A. Torres-Silva, C. Tenorio-Arguelles, R. García-Corona, D. A. Silva-González, S. Dominguez-Rodriguez, J. A. De Alba-Cruz, I. Nagore-Ancona, J. F. González-Luna, J. A. López-Bochm, K. A. |
author_sort | Martín-Pérez, J. A. |
collection | PubMed |
description | BACKGROUND: Gastric carcinoma (GC) with second primary malignancy (SPM) is the most frequent combination within the multiple primary malignancies (MPM) group. The presentation of a GC associated with a synchronized SPM in the kidney is extremely rare and unusual. This study presents a rare case of synchronous tumors, describes the main associated risk factors, and emphasizes the need to rule out SPM. MAIN BODY: We present the case of a 63-year-old Hispanic woman with a history of smoking, weight loss, and gastrointestinal (GI) bleeding. GC was diagnosed by endoscopy, and during her workup for metastatic disease, a synchronous SPM was noted in the left kidney. The patient underwent resection of both tumors with a satisfactory postoperative course. A systematic review of the literature was performed using the Medline/PubMed, Science Direct, Scopus, and Google Scholar databases. A search of the literature yielded 13 relevant articles, in which the following main risk factors were reported: the treatment utilized, the grade and clinical stage, histopathological report, and in some cases survival. It is concluded that advanced age (> 60 years) and smoking are the main associated risk factors. CONCLUSION: Gastric carcinoma is the second most frequent neoplasm of the GI tract and the main neoplasm that presents a SPM. MPM screening is recommended in patients with gastric cancer. The clinical discovery of MPM of renal origin is rare and hence the importance of the current report. |
format | Online Article Text |
id | pubmed-7709286 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-77092862020-12-02 Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature Martín-Pérez, J. A. Torres-Silva, C. Tenorio-Arguelles, R. García-Corona, D. A. Silva-González, S. Dominguez-Rodriguez, J. A. De Alba-Cruz, I. Nagore-Ancona, J. F. González-Luna, J. A. López-Bochm, K. A. J Med Case Rep Case Report BACKGROUND: Gastric carcinoma (GC) with second primary malignancy (SPM) is the most frequent combination within the multiple primary malignancies (MPM) group. The presentation of a GC associated with a synchronized SPM in the kidney is extremely rare and unusual. This study presents a rare case of synchronous tumors, describes the main associated risk factors, and emphasizes the need to rule out SPM. MAIN BODY: We present the case of a 63-year-old Hispanic woman with a history of smoking, weight loss, and gastrointestinal (GI) bleeding. GC was diagnosed by endoscopy, and during her workup for metastatic disease, a synchronous SPM was noted in the left kidney. The patient underwent resection of both tumors with a satisfactory postoperative course. A systematic review of the literature was performed using the Medline/PubMed, Science Direct, Scopus, and Google Scholar databases. A search of the literature yielded 13 relevant articles, in which the following main risk factors were reported: the treatment utilized, the grade and clinical stage, histopathological report, and in some cases survival. It is concluded that advanced age (> 60 years) and smoking are the main associated risk factors. CONCLUSION: Gastric carcinoma is the second most frequent neoplasm of the GI tract and the main neoplasm that presents a SPM. MPM screening is recommended in patients with gastric cancer. The clinical discovery of MPM of renal origin is rare and hence the importance of the current report. BioMed Central 2020-12-02 /pmc/articles/PMC7709286/ /pubmed/33261664 http://dx.doi.org/10.1186/s13256-020-02576-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Martín-Pérez, J. A. Torres-Silva, C. Tenorio-Arguelles, R. García-Corona, D. A. Silva-González, S. Dominguez-Rodriguez, J. A. De Alba-Cruz, I. Nagore-Ancona, J. F. González-Luna, J. A. López-Bochm, K. A. Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title | Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title_full | Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title_fullStr | Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title_full_unstemmed | Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title_short | Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
title_sort | gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709286/ https://www.ncbi.nlm.nih.gov/pubmed/33261664 http://dx.doi.org/10.1186/s13256-020-02576-6 |
work_keys_str_mv | AT martinperezja gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT torressilvac gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT tenorioarguellesr gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT garciacoronada gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT silvagonzalezs gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT dominguezrodriguezja gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT dealbacruzi gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT nagoreanconajf gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT gonzalezlunaja gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature AT lopezbochmka gastriccarcinomaandrenalcellcarcinomaasanatypicalpresentationofmultipleprimarymalignanciesacasereportandreviewoftheliterature |