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Early macrophage infiltrates impair pancreatic cancer cell growth by TNF-α secretion

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a grim disease with high mortality rates. Increased macrophage influx in PDAC is a common hallmark and associated with poor prognosis. Macrophages have high cellular plasticity, which can differentiate into both anti- and pro-tumorigenic propert...

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Detalles Bibliográficos
Autores principales: Tekin, Cansu, Aberson, Hella L., Bijlsma, Maarten F., Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709323/
https://www.ncbi.nlm.nih.gov/pubmed/33267818
http://dx.doi.org/10.1186/s12885-020-07697-1