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Early macrophage infiltrates impair pancreatic cancer cell growth by TNF-α secretion
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a grim disease with high mortality rates. Increased macrophage influx in PDAC is a common hallmark and associated with poor prognosis. Macrophages have high cellular plasticity, which can differentiate into both anti- and pro-tumorigenic propert...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709323/ https://www.ncbi.nlm.nih.gov/pubmed/33267818 http://dx.doi.org/10.1186/s12885-020-07697-1 |