Cargando…
Functionalized silk spheres selectively and effectively deliver a cytotoxic drug to targeted cancer cells in vivo
BACKGROUND: Chemotherapy is often a first-line therapeutic approach for the treatment of a wide variety of cancers. Targeted drug delivery systems (DDSs) can potentially resolve the problem of chemotherapeutic drug off-targeting effects. Herein, we examined in vivo models to determine the efficacy o...
Autores principales: | Florczak, Anna, Deptuch, Tomasz, Lewandowska, Anna, Penderecka, Karolina, Kramer, Elzbieta, Marszalek, Andrzej, Mackiewicz, Andrzej, Dams-Kozlowska, Hanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709326/ https://www.ncbi.nlm.nih.gov/pubmed/33261651 http://dx.doi.org/10.1186/s12951-020-00734-y |
Ejemplares similares
-
Drug affinity and targeted delivery: double functionalization of silk spheres for controlled doxorubicin delivery into Her2-positive cancer cells
por: Kucharczyk, Kamil, et al.
Publicado: (2020) -
In vivo study of the immune response to bioengineered spider silk spheres
por: Deptuch, Tomasz, et al.
Publicado: (2022) -
Cellular uptake, intracellular distribution and degradation of Her2-targeting silk nanospheres
por: Florczak, Anna, et al.
Publicado: (2019) -
Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy
por: Florczak, Anna, et al.
Publicado: (2021) -
The method of purifying bioengineered spider silk determines the silk sphere properties
por: Jastrzebska, Katarzyna, et al.
Publicado: (2016)