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Nebivolol combined with tetrahydrobiopterin affects diastolic function in spontaneously hypertensive rats via the nitric oxide/cyclic guanosine monophosphate signalling pathway

BACKGROUND: Hypertension is the the primary cause of diastolic heart failure. Oxidative stress plays an important role in cardiac diastolic dysfunction caused by hypertension. The occurrence of oxidative stress is related to the level of nitric oxide (NO) in the body. Tetrahydrobiopterin (BH4) is an...

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Detalles Bibliográficos
Autores principales:	Guan, Xiaoli, Guan, Xiaoying, Lu, Changhong, Shang, Bo, Zhao, Yuan, Meng, Ying, Zhang, Zhengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709331/ https://www.ncbi.nlm.nih.gov/pubmed/33267901 http://dx.doi.org/10.1186/s40360-020-00460-z

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