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Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats

BACKGROUND: Neuronal apoptosis plays a critical event in the pathogenesis of early brain injury after subarachnoid hemorrhage (SAH). This study investigated the roles of Tauroursodeoxycholic acid (TUDCA) in attenuate neuronal apoptosis and underlying mechanisms after SAH. METHODS: Sprague–Dawley rat...

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Detalles Bibliográficos
Autores principales:	Wu, Huihui, Yu, Nini, Wang, Xia, Yang, Yina, Liang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709410/ https://www.ncbi.nlm.nih.gov/pubmed/33261652 http://dx.doi.org/10.1186/s40659-020-00323-1

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