Simvastatin add-on to escitalopram in patients with comorbid obesity and major depression (SIMCODE): study protocol of a multicentre, randomised, double-blind, placebo-controlled trial

INTRODUCTION: Major depressive disorder (MDD) and obesity are both common disorders associated with significant burden of disease worldwide. Importantly, MDD and obesity often co-occur, with each disorder increasing the risk for developing the other by about 50%–60%. Statins are among the most presc...

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Detalles Bibliográficos
Autores principales: Otte, Christian, Chae, Woo Ri, Nowacki, Jan, Kaczmarczyk, Michael, Piber, Dominique, Roepke, Stefan, Märschenz, Stefanie, Lischewski, Sandra, Schmidt, Sein, Ettrich, Barbara, Grabe, Hans Joergen, Hegerl, Ulrich, Hinkelmann, Kim, Hofmann, Tobias, Janowitz, Deborah, Junghanns, Klaus, Kahl, Kai G., Klein, Jan Philipp, Krueger, Tillmann H. C., Leicht, Gregor, Prvulovic, David, Reif, Andreas, Schoettle, Daniel, Strauss, Maria, Westermair, Anna, Friede, Tim, Gold, Stefan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Mental Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709515/
https://www.ncbi.nlm.nih.gov/pubmed/33262189
http://dx.doi.org/10.1136/bmjopen-2020-040119

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