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Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration-resistant prostate cancer

Castration-resistant prostate cancer (CRPC) treatment still remains difficult. The aim of the present study was to determine the antitumour efficacy of the MutT homolog 1 (MTH1) inhibitor, TH1579, against castration-resistant prostate cancer. PC-3 and DU-145 prostate cancer cells were treated with d...

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Detalles Bibliográficos
Autores principales: Hu, Mingqiu, Ning, Jing, Mao, Likai, Yu, Yuanyuan, Wu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709546/
https://www.ncbi.nlm.nih.gov/pubmed/33281973
http://dx.doi.org/10.3892/ol.2020.12324