Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis

APRIN is a putative tumor suppressor whose expression is low in a variety of cancer cells. While decreased expression of APRIN leads to increased cell proliferation, unfavorable diagnosis or metastases in various cancer types, there is limited knowledge on the cellular mechanism of APRIN in cellular...

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Detalles Bibliográficos
Autores principales: Sohn, Min-Shik, Kang, Miae, Kang, Seong-Man, Bae, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709549/
https://www.ncbi.nlm.nih.gov/pubmed/33281966
http://dx.doi.org/10.3892/ol.2020.12317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709549/
https://www.ncbi.nlm.nih.gov/pubmed/33281966
http://dx.doi.org/10.3892/ol.2020.12317

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