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Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes

(1) Background: COVID-19 has become a global pandemic and older patients present higher mortality rates. However, studies on the characteristics of this population set are limited. The objective of this study is to describe clinical characteristics and outcomes of older patients hospitalized with CO...

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Autores principales: Steinmeyer, Zara, Vienne-Noyes, Sara, Bernard, Marc, Steinmeyer, Armand, Balardy, Laurent, Piau, Antoine, Sourdet, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709587/
https://www.ncbi.nlm.nih.gov/pubmed/32992602
http://dx.doi.org/10.3390/geriatrics5040065
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author Steinmeyer, Zara
Vienne-Noyes, Sara
Bernard, Marc
Steinmeyer, Armand
Balardy, Laurent
Piau, Antoine
Sourdet, Sandrine
author_facet Steinmeyer, Zara
Vienne-Noyes, Sara
Bernard, Marc
Steinmeyer, Armand
Balardy, Laurent
Piau, Antoine
Sourdet, Sandrine
author_sort Steinmeyer, Zara
collection PubMed
description (1) Background: COVID-19 has become a global pandemic and older patients present higher mortality rates. However, studies on the characteristics of this population set are limited. The objective of this study is to describe clinical characteristics and outcomes of older patients hospitalized with COVID-19. (2) Methods: This retrospective cohort study was conducted from March to May 2020 and took place in three acute geriatric wards in France. Older patients hospitalized for COVID-19 infections were included. We collected clinical, radiological, and laboratory outcomes. (3) Results: Ninety-four patients were hospitalized and included in the final analysis. Mean age was 85.5 years and 55% were female. Sixty-four (68%) patients were confirmed COVID-19 cases and 30 (32%) were probable. A majority of patients were dependent (77%), 45% were malnourished, and the mean number of comorbidities was high in accordance with the CIRS-G score (12.3 ± 25.6). The leading causes of hospitalization were fever (30%), dyspnea (28%), and geriatric syndromes (falls, delirium, malaise) (18%). Upon follow-up, 32% presented acute respiratory failure and 30% a geriatric complication. Frailty and geriatric characteristics were not correlated with mortality. Acute respiratory failure (p = 0.03) and lymphopenia (p = 0.02) were significantly associated with mortality. (4) Conclusions: Among older patients hospitalized with COVID-19, clinical presentations were frequently atypical and complications occurred frequently. Frailty and geriatric characteristics were not correlated with mortality.
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spelling pubmed-77095872020-12-03 Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes Steinmeyer, Zara Vienne-Noyes, Sara Bernard, Marc Steinmeyer, Armand Balardy, Laurent Piau, Antoine Sourdet, Sandrine Geriatrics (Basel) Article (1) Background: COVID-19 has become a global pandemic and older patients present higher mortality rates. However, studies on the characteristics of this population set are limited. The objective of this study is to describe clinical characteristics and outcomes of older patients hospitalized with COVID-19. (2) Methods: This retrospective cohort study was conducted from March to May 2020 and took place in three acute geriatric wards in France. Older patients hospitalized for COVID-19 infections were included. We collected clinical, radiological, and laboratory outcomes. (3) Results: Ninety-four patients were hospitalized and included in the final analysis. Mean age was 85.5 years and 55% were female. Sixty-four (68%) patients were confirmed COVID-19 cases and 30 (32%) were probable. A majority of patients were dependent (77%), 45% were malnourished, and the mean number of comorbidities was high in accordance with the CIRS-G score (12.3 ± 25.6). The leading causes of hospitalization were fever (30%), dyspnea (28%), and geriatric syndromes (falls, delirium, malaise) (18%). Upon follow-up, 32% presented acute respiratory failure and 30% a geriatric complication. Frailty and geriatric characteristics were not correlated with mortality. Acute respiratory failure (p = 0.03) and lymphopenia (p = 0.02) were significantly associated with mortality. (4) Conclusions: Among older patients hospitalized with COVID-19, clinical presentations were frequently atypical and complications occurred frequently. Frailty and geriatric characteristics were not correlated with mortality. MDPI 2020-09-27 /pmc/articles/PMC7709587/ /pubmed/32992602 http://dx.doi.org/10.3390/geriatrics5040065 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Steinmeyer, Zara
Vienne-Noyes, Sara
Bernard, Marc
Steinmeyer, Armand
Balardy, Laurent
Piau, Antoine
Sourdet, Sandrine
Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title_full Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title_fullStr Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title_full_unstemmed Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title_short Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes
title_sort acute care of older patients with covid-19: clinical characteristics and outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709587/
https://www.ncbi.nlm.nih.gov/pubmed/32992602
http://dx.doi.org/10.3390/geriatrics5040065
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