Cargando…

Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study

Introduction: dementia increases the risk of falls by 2–3 times and cognitively impaired patients are three times more likely to have hip fracture following a fall when compared to cognitively intact individuals. However, there is not enough evidence that explores the relationship between dementia a...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Inderpal, Duric, Daniel, Motoc, Alfe, Edwards, Chris, Anwar, Anser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709649/
https://www.ncbi.nlm.nih.gov/pubmed/33266236
http://dx.doi.org/10.3390/geriatrics5040099
_version_ 1783617795664117760
author Singh, Inderpal
Duric, Daniel
Motoc, Alfe
Edwards, Chris
Anwar, Anser
author_facet Singh, Inderpal
Duric, Daniel
Motoc, Alfe
Edwards, Chris
Anwar, Anser
author_sort Singh, Inderpal
collection PubMed
description Introduction: dementia increases the risk of falls by 2–3 times and cognitively impaired patients are three times more likely to have hip fracture following a fall when compared to cognitively intact individuals. However, there is not enough evidence that explores the relationship between dementia and fragility fractures. The aim of this study is to explore the relationships of prevalent fragility fracture in patients with dementia admitted with an acute illness to the hospital. Methods: the existing Health Board records were reviewed retrospectively for all patients admitted diagnosed with dementia in the year 2016. All patients were followed up for a maximum of three years. All of the the dementia patients were divided into three groups: group 1—“no fractures”; group 2—“all fractures”; group 3—“fragility fractures”. Clinical outcomes were analysed for hospital stay, discharge destination (new care home), post-discharge hip fracture data, and mortality. Results: dementia patients with a prevalent fracture were significantly older, 62% were women. A significantly higher proportion of dementia patients with prevalent fractures were care home residents and taking a significantly higher number of medications. The mean Charlson comorbidity index was similar in patients with or without fracture. Dementia patients with a prevalent fracture required a new care home and this is significantly higher when compared to those with no fracture. Mortality at one year and three year was not statistically different in patients with or without prevalent fractures. A significantly higher number (21.5%) of dementia patients with prevalent fragility fracture sustained a new hip fracture when compared to those with no prevalent osteoporotic fracture (2.9%) over the three years follow up (p < 0.0001). Conclusion: dementia patients with a prevalent fragility fracture is associated with a statistically significant higher risk of a new care home placement following acute hospital admission. This sub-group is also at risk of a new hip fracture in the next three years. Whilst clinical judgement remains crucial in the care of frail older people, it is prudent to consider medical management of osteoporosis in dementia if deemed to be beneficial following the comprehensive geriatric assessment.
format Online
Article
Text
id pubmed-7709649
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77096492020-12-03 Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study Singh, Inderpal Duric, Daniel Motoc, Alfe Edwards, Chris Anwar, Anser Geriatrics (Basel) Article Introduction: dementia increases the risk of falls by 2–3 times and cognitively impaired patients are three times more likely to have hip fracture following a fall when compared to cognitively intact individuals. However, there is not enough evidence that explores the relationship between dementia and fragility fractures. The aim of this study is to explore the relationships of prevalent fragility fracture in patients with dementia admitted with an acute illness to the hospital. Methods: the existing Health Board records were reviewed retrospectively for all patients admitted diagnosed with dementia in the year 2016. All patients were followed up for a maximum of three years. All of the the dementia patients were divided into three groups: group 1—“no fractures”; group 2—“all fractures”; group 3—“fragility fractures”. Clinical outcomes were analysed for hospital stay, discharge destination (new care home), post-discharge hip fracture data, and mortality. Results: dementia patients with a prevalent fracture were significantly older, 62% were women. A significantly higher proportion of dementia patients with prevalent fractures were care home residents and taking a significantly higher number of medications. The mean Charlson comorbidity index was similar in patients with or without fracture. Dementia patients with a prevalent fracture required a new care home and this is significantly higher when compared to those with no fracture. Mortality at one year and three year was not statistically different in patients with or without prevalent fractures. A significantly higher number (21.5%) of dementia patients with prevalent fragility fracture sustained a new hip fracture when compared to those with no prevalent osteoporotic fracture (2.9%) over the three years follow up (p < 0.0001). Conclusion: dementia patients with a prevalent fragility fracture is associated with a statistically significant higher risk of a new care home placement following acute hospital admission. This sub-group is also at risk of a new hip fracture in the next three years. Whilst clinical judgement remains crucial in the care of frail older people, it is prudent to consider medical management of osteoporosis in dementia if deemed to be beneficial following the comprehensive geriatric assessment. MDPI 2020-11-30 /pmc/articles/PMC7709649/ /pubmed/33266236 http://dx.doi.org/10.3390/geriatrics5040099 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Singh, Inderpal
Duric, Daniel
Motoc, Alfe
Edwards, Chris
Anwar, Anser
Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title_full Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title_fullStr Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title_full_unstemmed Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title_short Relationship of Prevalent Fragility Fracture in Dementia Patients: Three Years Follow up Study
title_sort relationship of prevalent fragility fracture in dementia patients: three years follow up study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709649/
https://www.ncbi.nlm.nih.gov/pubmed/33266236
http://dx.doi.org/10.3390/geriatrics5040099
work_keys_str_mv AT singhinderpal relationshipofprevalentfragilityfractureindementiapatientsthreeyearsfollowupstudy
AT duricdaniel relationshipofprevalentfragilityfractureindementiapatientsthreeyearsfollowupstudy
AT motocalfe relationshipofprevalentfragilityfractureindementiapatientsthreeyearsfollowupstudy
AT edwardschris relationshipofprevalentfragilityfractureindementiapatientsthreeyearsfollowupstudy
AT anwaranser relationshipofprevalentfragilityfractureindementiapatientsthreeyearsfollowupstudy