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Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway

Diastolic dysfunction is condition of a stiff ventricle and a function of aging. It causes significant cardiovascular mortality and morbidity, and in fact, three million Americans are currently suffering from this condition. To date, all the pharmacological clinical trials have been negative. The la...

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Detalles Bibliográficos
Autores principales: Moudgil, Rohit, Samra, Gursharan, Ko, Kyung Ae, Vu, Hang Thi, Thomas, Tamlyn N., Luo, Weijia, Chang, Jiang, Reddy, Anilkumar K., Fujiwara, Keigi, Abe, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709875/
https://www.ncbi.nlm.nih.gov/pubmed/33330654
http://dx.doi.org/10.3389/fcvm.2020.594123