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Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic‐Like Behaviors

STING is known as a central adaptor for sensing cytosolic DNA sensing. Recent studies have provided evidence that STING response is divergent among different cell types. Here, this work demonstrates that STING controls neural progenitor cells (NPCs) by sensing DNA damage in NPCs. The deletion of STI...

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Detalles Bibliográficos
Autores principales: Zhang, Dongming, Liu, Chang, Li, Hong, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710002/
https://www.ncbi.nlm.nih.gov/pubmed/33304758
http://dx.doi.org/10.1002/advs.202002117