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M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

Xenophagy is an important cellular defence mechanism against cytosol-invading pathogens, such as Mycobacterium tuberculosis (Mtb). Activation of xenophagy in macrophages targets Mtb to autophagosomes; however, how Mtb is targeted to autophagosomes in human macrophages at a high spatial and temporal...

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Detalles Bibliográficos
Autores principales:	Bernard, Elliott M., Fearns, Antony, Bussi, Claudio, Santucci, Pierre, Peddie, Christopher J., Lai, Rachel J., Collinson, Lucy M., Gutierrez, Maximiliano G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710011/ https://www.ncbi.nlm.nih.gov/pubmed/32938685 http://dx.doi.org/10.1242/jcs.252973

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