Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

Inflammatory bowel diseases (IBDs) cause significant morbidity and mortality. Aberrant NF-κB signalling is strongly associated with these conditions, and several established drugs influence the NF-κB signalling network to exert their effect. This study aimed to identify drugs that alter NF-κB signal...

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Detalles Bibliográficos
Autores principales: Lloyd, Katie, Papoutsopoulou, Stamatia, Smith, Emily, Stegmaier, Philip, Bergey, Francois, Morris, Lorna, Kittner, Madeleine, England, Hazel, Spiller, Dave, White, Mike H. R., Duckworth, Carrie A., Campbell, Barry J., Poroikov, Vladimir, Martins dos Santos, Vitor A. P., Kel, Alexander, Muller, Werner, Pritchard, D. Mark, Probert, Chris, Burkitt, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710021/
https://www.ncbi.nlm.nih.gov/pubmed/32958515
http://dx.doi.org/10.1242/dmm.044040

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